SORBITOL (SOR buh tol) treats occasional constipation. It works by increasing the amount of water your intestine absorbs. This softens the stool, making it easier to have a bowel movement. It also increases pressure, which prompts the muscles in your intestines to move stool. It belongs to a group of medications called laxatives.
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This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
They need to know if you have any of these conditions:
Take this medication by mouth. Take it as directed on prescription label at the same time every day. Use a specially marked oral syringe, spoon, or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. You can take it with or without food. If it upsets your stomach, take it with food.
This medication may also be used rectally with an enema. Follow the directions on the label. Wash your hands before and after use. Remove top from enema. Lubricate the tip of the bottle. Lie on your side with your lower leg straightened out and your upper leg bent forward towards your stomach. Lift upper buttock to expose the rectal area. Gently insert enema tip into the rectum. Squeeze the bottle until empty. Wait a few seconds before removing the bottle. Hold buttocks together for a few seconds. Remain lying down for about 15 minutes to avoid having the medication come out.
Talk to your care team about the use of this medication in children.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
This does not apply. This medication is not for regular use, and should only be used as needed.
Interactions are not expected.
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
Tell your care team if your symptoms do not start to get better or if they get worse. Do not use this medication for longer than directed by your care team. This medication can be habit-forming. Long-term use can make your body depend on the laxative for regular bowel movements, damage the bowel, cause malnutrition, and cause problems with the amounts of water and salts in your body. If your constipation keeps returning, check with your care team.
Do not use with any other laxatives. Drink fluids as directed to prevent dehydration. See your care team right away if you do not have a bowel movement after using this medication.
Side effects that you should report to your care team as soon as possible:
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-.
Keep out of the reach of children and pets.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Get rid of any unused medication after the expiration date.
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To get rid of medications that are no longer needed or have expired:
NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider.
Sorbitol is a naturally occurring sweetener synthetically extracted from glucose. Owing to its low calorific value, it is used in pharmaceutical products, sugar-free foods, and oral care products such as mouth fresheners and toothpastes. It is prescribed for use by diabetes patients as it has a lesser tendency to increase the sugar level in the blood.
Consumption of sorbitol gives a cooling sensation in the mouth with almost no aftertaste. It helps to maintain the high quality of food products by retaining moisture, improving the texture, and acts as a crystallization modifier, a softening agent, and a viscosity controller. It is an important ingredient in confectionery items and food that need to be stored for some time. Sorbitol is a natural constituent of fruits such as apples and pears; dry fruits such as prunes and raisins; stoned fruits like apricots and peaches, and berries of the family of the Sorbus tree.
In , a report by the European Union’s Scientific Committee on food stated that intake of above 50 g of sorbitol per day may result in diarrhea. It also stated that food containing greater than 10% of sorbitol may be harmful to health and can have a laxative effect. Polyols are alcohol sugars and sorbitol is a type of polyol. In Europe, polyols are banned in soft drinks because of their laxative effects.
In , the European Food Safety Authority submitted a health report on polyols such as sorbitol and concluded that they could be used for improving dental health and for repairing teeth enamel. EFSA has no fixed safety margin for the daily intake of sorbitol.
Sorbitol was first used in the USA by the food industry in . The Generally Recognized as Safe (GRAS) list of Food and Drug Administration (FDA) suggests a tolerance of 7% of sorbitol in foods. FDA studies have found no toxicity and determine the normal level of consumption of sorbitol to be 25 g daily in two doses. No carcinogenic effects were found in experiments on sorbitol. Animal studies involving rats injected with sorbitol showed no tumor incidences at the injection site.
Sorbitol has been declared safe for use by a number of scientific studies. The Joint Food and Agriculture Organization (JECFA) has categorized the acceptable daily intake (ADI) of sorbitol as “not specified,” which is actually the safest category for any food ingredient. There is no fixed upper margin for the intake level of sorbitol. However, FDA suggests that if the daily intake level of sorbitol exceeds 30 g per day, it may result in serious symptoms. People suffering from nausea, vomiting, or abdominal pain should avoid sweeteners like sorbitol, while pregnant and breast-feeding women should consult their physician before use.
Sorbitol is best used when stored at the normal atmospheric temperature (15°C to 30°C). Temperatures below this level may lead to thickening of sorbitol, and it should not be allowed to freeze.
The side effects of consumption of sorbitol are mild; the main health concern faced is gastrointestinal disturbances, as sorbitol does not get completely digested in the small intestine.
The small intestine absorbs sorbitol in small amounts, which are then converted to fructose. The presence of the excess amount of the remaining sorbitol may result in diarrhea. Excessive sorbitol usage may result in gastrointestinal complexities such as flatulence, bloating, cramping, and other abdominal discomforts. Sorbitol intake may cause serious problems in people who are highly sensitive to laxative effects caused by it.
Other side effects that may arise due to sorbitol usage are listed below:
Consultation with the physician is suggested if any of the above symptoms arise.
Cavities
Generally, sorbitol does not lead to tooth decay. Starches and sugars in foods are split up by oral bacteria and these bacteria release acids. Such acids gradually destroy tooth enamel if they are not rinsed properly. Sorbitol and other sugar acids or polyols react against bacterial metabolism and hence there is no decay in the enamel.
Diabetes
Diabetic children are suggested to manage their blood lipids, glucose, and weight. As sorbitol is absorbed gradually and partially, the reaction of blood glucose and combined insulin is decreased. Also, the calorific value of sorbitol is two-thirds of normal sugar, so it is helpful in managing the body mass index among children.
However, the excess intake of this sweetener might have a negative impact on children.
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