3,5-Difluorophenylboronic acid, CAS 156545-07-2, is an aryl boronic acid used primarily as a building block for carbon–carbon bond-forming reactions, especially Suzuki–Miyaura coupling. Its commonly reported molecular formula is C6H5BF2O2, with a molecular weight of approximately 157.91 g/mol. I recommend that buyers confirm identity, assay, water content, appearance, packaging, documentation, and delivery expectations before placing an order, because the most suitable specification depends on the intended synthesis and process scale.
At Maison Chemical, I support B2B buyers by clarifying product requirements, reviewing available quality documents, preparing quotations, and coordinating shipment arrangements for 3,5-Difluorophenylboronic acid. I do not treat a catalog name alone as a complete purchasing specification. Instead, I encourage procurement, quality, and R&D teams to align the required grade and documentation before commercial confirmation.
This guide is intended for pharmaceutical and agrochemical researchers, medicinal chemistry teams, custom synthesis companies, chemical distributors, and procurement specialists sourcing an aromatic boronic acid. It is also useful for laboratories moving from milligram-scale experimentation to gram or kilogram-level planning. Each group may require a different balance of purity, lot size, analytical support, packaging, and delivery flexibility.
Buyers should involve both the technical user and the purchasing department at an early stage. The chemist can define the reaction and impurity sensitivity, while procurement can evaluate minimum order quantity, commercial terms, supply continuity, and shipping requirements. This combined review reduces the risk of ordering material that is chemically suitable but operationally inconvenient.
3,5-Difluorophenylboronic acid contains an aryl boronic acid group and two fluorine substituents on the benzene ring. In a typical Suzuki–Miyaura coupling, the boronic acid functionality serves as the transferable aryl component, while the fluorinated ring remains part of the final product. The exact reaction performance depends on the reaction partners, catalyst system, base, solvent, temperature, work-up, and purification method.
The two fluorine atoms can affect the electronic properties of the aromatic ring, which may be relevant when researchers are designing analogues or optimizing a synthetic route. However, I recommend treating these electronic effects as a route-development consideration rather than a guarantee of improved yield. Reaction suitability should be confirmed experimentally with the buyer’s specific substrate and process conditions.
| Item | Typical purchasing reference | Why it matters |
|---|---|---|
| Product name | 3,5-Difluorophenylboronic acid | Confirms the intended aromatic boronic acid |
| CAS number | 156545-07-2 | Reduces ambiguity during sourcing and import documentation |
| Molecular formula | C6H5BF2O2 | Supports identity review and theoretical calculations |
| Molecular weight | Approximately 157.91 g/mol | Used for weighing, molar calculations, and formulation planning |
The table provides identity-level reference information, not a substitute for a batch-specific certificate of analysis. Buyers should request the actual specification and analytical results for the lot offered. If a project requires a particular assay, residual solvent limit, water limit, or particle form, those requirements should be stated before quotation.
Commercial requirements for this product may differ according to the buyer’s use. A research purchaser may need a small quantity with standard analytical documentation, while a process-development team may require a defined assay, impurity profile, packaging configuration, and repeat-lot consistency. A distributor may instead focus on stable packaging, labeling, export paperwork, and a specification suitable for resale.
I recommend separating mandatory requirements from preferred requirements. Mandatory requirements may include the correct CAS number, a minimum assay, acceptable appearance, a defined retest or shelf-life policy, and delivery to a specified country. Preferred requirements may include a particular package size, additional chromatographic data, a specific incoterm, or a reserved production window.
Documentation availability can vary by product grade, order size, destination, and production status. I therefore advise buyers to confirm the document package in writing rather than assuming that every lot includes the same records. If a customer requires a quality agreement or additional testing, the request should be reviewed before the purchase order is finalized.
For medicinal chemistry and discovery research, the key question is usually whether the material is appropriate for a planned coupling and available in a practical pack size. For process development, buyers should place more emphasis on lot-to-lot consistency, impurity control, analytical comparability, and supply continuity. For commercial manufacturing, qualification procedures and change-control expectations may become more important than the initial sample price.
Storage and handling should follow the supplier’s current SDS and product documentation. Boronic acids can be sensitive to environmental and handling conditions, and the actual stability profile may depend on packaging, moisture exposure, temperature, and storage duration. I recommend keeping the material in its original, properly closed container and asking for specific storage instructions before internal distribution.
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Start with the exact name and CAS number, intended use, required quantity, target assay, and any impurity or water limits. Include whether the material is for route screening, process development, analytical work, or manufacturing support. A clear technical brief allows the supplier to propose a relevant grade instead of issuing a generic quotation.
Ask suppliers to quote the same package sizes and commercial terms so that price comparisons are meaningful. The inquiry should identify the requested quantity in grams or kilograms, destination country, packaging preference, required documents, and desired delivery window. Buyers should also ask whether the quoted material is available from stock, scheduled for production, or subject to confirmation.
Compare the offered specification with the project requirement, not only with the product title. Review the CAS number, formula, molecular weight, assay method, appearance criteria, impurity controls, and certificate format. If the project depends on repeat supply, ask how future lots will be evaluated and whether the supplier can discuss a longer-term supply plan.
Before issuing a purchase order, confirm the minimum order quantity, pack configuration, lead-time estimate, payment terms, shipping method, incoterm, and responsibility for destination clearance. Lead time should be treated as an order-specific estimate rather than a universal promise. A written confirmation is especially important when the material is needed for a time-sensitive synthesis campaign.
The price of 3,5-Difluorophenylboronic acid can vary with order quantity, purity requirement, packaging, production status, analytical work, destination, and freight conditions. A low unit price may not represent the lowest total procurement cost if it requires an unsuitable pack size, additional testing, or a longer delivery schedule. I recommend evaluating material cost, documentation cost, freight, import handling, and potential qualification work together.
Minimum order quantity is not always fixed across all purchasing situations. Small research quantities may be available under different commercial conditions from bulk or repeat orders, while custom packaging or additional testing may affect the final quotation. Buyers should state their expected annual demand when possible, because demand visibility may help suppliers assess a more suitable supply arrangement.
Another frequent mistake is treating a supplier’s stated availability as a guaranteed delivery date. Availability can change with stock allocation, quality release, production scheduling, and transport conditions. I suggest asking for a current availability statement and reconfirming the schedule before payment or shipment.
Maison Chemical provides a practical point of contact for buyers sourcing 3,5-Difluorophenylboronic acid for research, development, distribution, and manufacturing-related needs. I can help organize product identity details, clarify the required specification, coordinate document requests, and prepare a quotation based on quantity and destination. For repeat projects, I can also discuss forecast information and the buyer’s preferred supply process.
Our role is to communicate what is available and what must be confirmed for each order. We do not replace the buyer’s internal qualification, regulatory review, or process validation. Instead, we aim to make those activities easier by establishing a clear technical and commercial basis before shipment.
If you are ready to purchase 3,5-Difluorophenylboronic acid CAS 156545-07-2, prepare an inquiry containing the required quantity, target specification, application stage, destination, packaging preference, requested documents, and desired delivery window. If you have an existing specification or certificate format, include it with the inquiry so that the supplier can review it accurately. This approach usually produces a more useful quotation than a request containing only the chemical name.
Contact Maison Chemical with your purchasing requirements for 3,5-Difluorophenylboronic acid. I will help you confirm the product identity, review the applicable documentation, and evaluate the most suitable supply option for your project. The best purchasing decision is the one that aligns chemical suitability, documented quality, logistics, and total cost before the order is released.
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