Dissolving Lip Fillers: Natural and Injection Method Explained

28 Feb.,2024


Lip fillers are one of the most popular non-surgical cosmetic procedures, and for good reason: in just half an hour, lip fillers provide subtly enhanced or visibly bigger lips. The results are usually stunning, and you can maintain them with regular treatments.

But what if you don’t like the results?

Luckily, you have options. Read on to find out how you can dissolve lip fillers.

How Can You Dissolve Lip Fillers?

Patients who experience lip asymmetries, lumps and nodules, oversized lips, or other undesired effects of the treatment can dissolve lip fillers in two ways – naturally or with lip filler dissolving injections administered by a licensed medical professional.

The Natural Way

FDA-approved lip fillers are made from hyaluronic acid, a sugar compound that appears naturally in the body. It gradually breaks down on its own, providing temporary results that last 6 to 12 months.

Also, lips move more than other facial areas, making lip fillers dissolve more quickly than other types of filler.  

Patients who are unhappy with the results can wait until the filler dissolves naturally or request a filler dissolving injection.


Hyaluronidase is an enzyme found in many organisms and it is used in medicine for various purposes. The cosmetics industry uses hyaluronidase injections to speed up hyaluronic acid breakdown.

The enzyme is injected into the patient’s lips in a procedure similar to injecting lip fillers. The procedure is safe when performed by experienced medical professionals.

Patients see the effects of the procedure within a few days.

Sometimes dermal fillers don’t dissolve fully or evenly after one procedure. If that happens, you will need to repeat the hyaluronidase treatment. 

Which Lip Fillers Can Be Dissolved?

FDA-approved dermal fillers are made from hyaluronic acid, poly-L-lactic acid, and calcium hydroxylapatite. All of them dissolve naturally, but the effects can last for up to two years.

Only hyaluronic acid fillers can be dissolved using a hyaluronidase injection. Since all approved lip fillers are made from HA, you should be able to reverse the effects of the treatment quickly.

What Does the Procedure for Dissolving Lip Fillers Look Like

Medical providers use hyaluronidase in off-label treatments to degrade hyaluronic acid fillers. Often, the procedure for dissolving lip fillers is the only option for patients whose lip filler treatment was performed by an untrained, non-medical cosmetic practitioner.

The Procedure

The lip filler dissolving treatment starts with a patch test. The medical provider administers a needle into the patient’s arm with a dose of hyaluronidase to see if they develop an allergic reaction. If no allergic reaction occurs, the provider undergoes the lip filler dissolving procedure after half an hour.

The provider first numbs the patient’s lips with a numbing cream. Then they inject hyaluronidase using several small needles. The procedure takes 10-15 minutes.

The enzyme breaks down dermal fillers gradually. The effects typically appear within 48 hours after the procedure but, in some cases, it may take up to two weeks.

How Long Does It Take to Dissolve Lip Fillers?

Lip fillers are not permanent. Patients who want their fillers dissolved naturally need to wait between 6 and 12 months.

A reverse treatment using a hyaluronidase injection dissolves lip fillers within a few days.

Things You Should Know Before Dissolving Lip Fillers

Like any other treatment that includes needles and injections, dissolving lip fillers carries potential risks and side-effects. Before you book the procedure, here’s what you should know.

Is Dissolving Lip Fillers Painful?

Lips are full of nerve endings and sensitive to pain. That is why it may sting a little when the injection is inserted into the lips. Most aesthetic professionals apply a numbing cream before administering hyaluronidase.

Can I Dissolve Lip Fillers at Home?

You cannot dissolve lip fillers at home. Only licensed medical professionals can administer the enzyme hyaluronidase. However, you can wait for your dermal fillers to dissolve on their own.

What Are the Risks of Dissolving Lip Fillers?

The biggest risk is that hyaluronidase can potentially degrade your natural hyaluronic acid rather than just the foreign filler. If that happens, you will have thinner lips than expected. That is why you should only let an experienced professional perform this treatment or wait for your lip fillers to dissolve naturally.

There is also a risk of an allergic reaction. Medical providers typically perform a patch test prior to the injection.

Are There Side-Effects of Dissolving Lip Fillers?

Swelling and bruising are common side effects of dissolving lip fillers with injections, but they subside within a few days.

On rare occasions, the lips become thinner than anticipated. This can be resolved with another round of fillers in a reputable med spa, such as Vibrant Skin Bar.


Patients who visit qualified medical providers to inject lip fillers are usually happy with the treatment.

However, if you experience unpleasant results, a hyaluronidase injection can help. Talk to our medical staff at Vibrant Skin Bar for advice on how to dissolve your lip filler and achieve your desired aesthetic goals.

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