Plasma Fibroblast Therapy: Procedure, Benefits, and Effectiveness

05 Jun.,2025

 

Plasma Fibroblast Therapy: Procedure, Benefits, and Effectiveness

Plasma fibroblast therapy, also called plasma skin resurfacing, is a skin treatment designed to improve the look of your skin by increasing the number of fibroblasts, the collagen- and protein-producing cells in your skin.

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Plasma fibroblast therapy is an aesthetic procedure some healthcare providers may offer as an alternative to laser, injections, or surgical therapies to tighten and improve the appearance of skin.

This therapy is fairly new to the facial and cosmetic treatment scene.

Keep reading to find out how it works and how much the procedure will set you back.

Plasma fibroblast therapy targets fibroblasts. These are collagen– and protein-producing cells in the dermis, the layer of skin just below your outermost skin layer.

Fibroblasts play an important role in helping skin wounds heal as well as maintaining skin firmness and tightness.

Plasma fibroblast therapy uses a pen-like device that discharges a high-frequency electric current to small areas of the skin.

The plasma tip doesn’t directly touch the skin, but instead releases a targeted current just above the skin. The hot current creates small holes, or micro-injuries, in the skin’s layer.

According to an article published in the PMFA journal, the thermal disruption, or heat damage, from plasma fibroblast therapy:

  • breaks down proteins in the skin
  • encourages tissue regeneration
  • stimulates fibroblast activity
  • causes tissue contraction (tightening)

Healthcare providers may also call this approach plasma skin resurfacing.

Plasma fibroblast therapy is a nonsurgical treatment that may be used to treat the following conditions:

  • acne scars
  • photo aging, including age spots
  • seborrheic keratosis
  • wrinkled skin, including the eyelids, neck, jawline, and above the lips

Cosmetic specialists may also use plasma fibroblast therapy as an alternative to lip fillers to make the lips look fuller.

Does it work?

When plasma fibroblast therapy is performed in a safe, controlled environment, it can:

  • improve skin texture
  • offer mild-to-moderate skin tightening effects
  • result in some degree of skin facial contour change

According to a article published in the journal Clinical, Cosmetic and Investigational Dermatology, the effects are expected to stimulate fibroblast production for up to 1 year after treatment.

However, there aren’t a lot of studies on plasma fibroblast therapy as it’s a relatively new aesthetic procedure.

One small study used plasma fibroblast therapies on eight participants.

Each participant received one full-face treatment every 3 weeks. At the study’s conclusion, patients reported a 37 percent reduction in facial wrinkling and a 68 percent overall improvement in facial appearance.

While the procedure may vary slightly based on where you’re having the treatment, the basic steps typically include:

  • Cleansing the skin and applying a topical anesthetic (numbing) cream. You may need to wait about 30 minutes for the numbing cream to take effect.
  • Treating the designated skin area with the plasma pen. The pen will create small arcs of microcurrents that make small scab-like dots on the skin.
  • A professional will remove the numbing cream and apply a cooling gel to minimize the tingling and burning sensation whenever possible.

The procedure usually takes about 30 to 60 minutes to perform.

Recovery

Once the procedure is completed, you can expect the small dots to scab over and fall off after about 1 week. Over the next couple of weeks, as your skin heals, it should appear tighter and firmer.

Some people may see benefits from one treatment, while others may require three treatments before they see results.

The best candidates for this procedure are people with mild-to-moderate skin wrinkling concerns.

You shouldn’t receive plasma fibroblast therapy if you:

  • are breastfeeding
  • are pregnant
  • have an allergy to topical anesthetic preparations
  • have an infection at the treatment site
  • are using isotretinoin for wrinkles or acne

In addition, if you have a history of keloids or hypertrophic scarring, it’s recommended that you approach plasma fibroblast therapy with caution.

It’s important to talk to a healthcare provider prior to the procedure to discuss your treatment goals and any potential concerns you may have given your overall health condition.

It’s very important that the healthcare provider performing the procedure establish realistic goals with you. While plasma fibroblast therapy can offer results, they aren’t likely to be as dramatic as a surgical procedure.

In addition, the procedure isn’t without side effects. Examples of side effects include:

  • redness
  • swelling
  • mild hypopigmentation (light spots)
  • mild hyperpigmentation (dark spots)
  • skin peeling and crusting

It’s worth noting that plasma fibroblast therapy isn’t legal in all parts of the world.

For example, Canada doesn’t currently authorize the use of plasma pens for cosmetic purposes.

Health Canada believes that plasma fibroblast therapy may pose health risks as the devices (and some of the aestheticians who use them) haven’t been evaluated for safety, effectiveness, or quality.

Don’t try this at home

Just because something is sold online doesn’t mean it’s safe. Some websites may sell pens that claim you can perform plasma fibroblast therapy at home.

This is never a good idea. There are no controls on how these pens are made, and they have the potential to cause significant harm, such as facial burns.

Plasma fibroblast therapy costs usually depend on who’s performing the procedure and what areas of your skin are being targeted.

For example, RAIN Spa in Rhinebeck, New York, reports plasma fibroblast therapy costs $600 to treat the undereye region, or $720 to treat the upper or lower lip.

If you’re interested in the treatment, you should ask your healthcare provider how many treatments you may need to see results as well as if the fee includes all costs, including those for numbing creams.

Plasma fibroblast therapy is a newer technique and therefore doesn’t currently have much evidence on its effectiveness.

However, it’s a technique that can tighten the skin without the need for invasive cosmetic procedures. Most people will require about 1 week of downtime and see results over the course of several weeks.

Meizi contains other products and information you need, so please check it out.

If you’re interested in plasma fibroblast therapy, talk to a healthcare provider about what to expect and whether the procedure is right for you.

Plasma Fibroblast Therapy Treatments in California

Introducing the revolutionary non-surgical plasma fibroblast therapy designed for effective and lasting skin rejuvenation.

From addressing acne scars and age spots to refining wrinkled zones like eyelids and the neck, this treatment targets the skin's fibroblast cells, enhancing firmness and tightness.

Using a plasma pen that delicately operates just above the skin's surface, this method induces micro-injuries to stimulate natural collagen production.

Enjoy revitalized, luminous skin right here in California. Eager for a transformative skin journey? Add plasma fibroblast therapy to your cart and check out to book your treatment today. You can also contact us to learn more.

Plasma fibroblast therapy targets cells within the skin called fibroblasts. These are collagen– and protein-producing cells in the dermis, the layer of skin just below your outermost skin layer.

Fibroblasts play an important role in helping skin wounds heal as well as maintaining skin firmness and tightness.

The plasma tip doesn’t directly touch the skin, but instead releases a targeted current just above the skin to create micro-injuries in the skin’s layer.

Plasma fibroblast is a non-invasive treatment designed to address wrinkles, sagging, and other age-related concerns, offering a non-surgical path to enhanced skin vitality. 

Plasma Fibroblast Therapy is a versatile treatment designed to address a range of skin concerns. It's particularly effective for those struggling with loose skin and sagging skin.

The procedure excels in maintaining skin firmness and tackling issues like acne scars, age-induced photo aging including prominent age spots, and seborrheic keratosis.

Further, its efficacy extends to treating wrinkled skin in delicate and prominent regions like the eyelids, neck, jawline, areas above the lip, abdomen, and even the belly button.

For anyone looking to rejuvenate their appearance, Plasma Fibroblast Therapy offers a comprehensive solution.

Individuals seeking effective skin tightening and a solution for reducing facial lines and wrinkles skin are ideal candidates for plasma fibroblast therapy.

Whether it's due to aging or other factors, those who desire a rejuvenated and firmer skin appearance can greatly benefit from this procedure. It is however essential to consult with an skincare specialist to determine if this treatment aligns with your skin health and aesthetic goals.

A typical plasma fibroblast therapy session can range from 30 minutes to 2 hours, depending on the treatment area and its size. Initial consultation, skin prep, and the application of a numbing agent can extend this duration. During your initial consultation, an aesthetic specialist will walk you through the treatment process. 

The neckline, especially the area under the chin and along the throat, is prone to showing early signs of aging like sagging and wrinkles. Plasma Fibroblast tightens and rejuvenates this region, restoring a youthful contour and reducing the appearance of "turkey neck."

Over time or post-pregnancy, the skin around the abdomen and belly button can become lax or wrinkled. Plasma Fibroblast is an effective treatment to tighten and firm this area, enhancing the overall tone and appearance of the stomach region.

The skin on and around the lips can lose volume and develop vertical lines over time. Plasma Fibroblast treatment can plump up the lips slightly and diminish the appearance of those vertical lines, granting the lips a fuller and more youthful look.

The number of plasma fibroblast treatments required varies based on individual skin concerns and desired outcomes. While many clients observe noticeable results after just one session, some may benefit from multiple treatments, especially for deeper wrinkles or more pronounced sagging.

It's crucial to consult with a specialist to determine the optimal number of sessions required to achieve your specific goals.

During a plasma fibroblast treatment, you will relax while your skincare provider uses a specialized plasma fibroblast device. The treatment begins with cleansing the targeted skin area, ensuring it's free from oils and impurities.

A numbing cream is then applied to minimize discomfort. Once the skin is prepped, the provider uses the device's tip to create micro-injuries or "dots" on the skin surface, triggering the body's natural healing response. This process stimulates the production of collagen and elastin, leading to tighter and rejuvenated skin.

Finally, a soothing ointment or cream is applied to assist with the healing process and protect the treated area.

Yes, plasma fibroblast is a non-invasive treatment that is typically considered safe when performed by certified professionals.

However, as with any cosmetic treatment, there are potential risks involved. Adherence to pre and post-treatment care can significantly reduce the chances of side effects. Always share your full medical history and any skin-related issues with our practitioners to ensure an informed and safe procedure.

At California Cosmetics, your safety and well-being are paramount. We invite you to schedule a consultation with our seasoned team to discuss if plasma fibroblast is the ideal solution for your aesthetic desires.

Post plasma fibroblast treatment, patients may experience temporary redness and minor swelling in the treated areas. Tiny crusts or scabs can form where the plasma pen has been applied, which naturally flake off over a week. Some may also notice a slight tightness or tingling sensation. It's essential to follow aftercare instructions to minimize risks and promote optimal healing.

In California, the average price range can be from $500 to $2,500 depending on the specific area being treated. Targeted areas like crow's feet might cost around $500, whereas larger zones like the abdomen could reach upwards of $2,500.

It's always best to consult with a certified provider in your area for an accurate estimate and to ensure the best possible results. The cost of plasma fibroblast therapy may vary based on the treatment area, location, the expertise of the practitioner and your unique goals.

Following a plasma fibroblast treatment, initial results can often be observed within a week as the skin starts its natural regeneration process. However, the most noticeable and lasting outcomes typically manifest over the next 4-6 weeks. As collagen production is boosted, the skin becomes tighter, and desired improvements in texture and tone become more evident.

Plasma fibroblast therapy offers lasting results, with many individuals experiencing improvements for up to 2-3 years after treatment.

The longevity can vary based on individual skin types, aftercare, and an individual’s normal ageing process. Using ideal skin care post-treatment (including sun protection) and also play an essential role in the longevity of results.

Choosing the best treatment from the vast array of skin rejuvenation options can be daunting. Each method offers distinct advantages tailored for specific skin issues. Below, we compare Plasma Fibroblast with other common skin treatments to provide a better understanding. For tailored recommendations, please consult with our experts.

Both plasma fibroblast and RF Microneedling are designed to stimulate collagen production and rejuvenate the skin. While Plasma Fibroblast creates micro-injuries using electric arcs to tighten the skin, RF microneedling combines microneedling with radiofrequency to enhance skin's elasticity and reduce scars. The choice between them depends on the patient's specific needs and desired outcomes. A detailed consultation can guide individuals in making the most informed decision.

Plasma fibroblast and fractional laser treatments both aim to improve skin texture and tone. While plasma fibroblast uses plasma energy to stimulate fibroblasts for collagen production, fractional laser treatments employ light energy to create tiny microthermal zones, promoting skin healing and renewal. Our specialists can help you determine which treatment aligns best with your skincare goals during your consultation.

Plasma Fibroblast is a specialized cosmetic procedure and should be performed by trained and certified professionals. Those experienced in cosmetic procedures, particularly with the intricate use of the plasma pen, are ideal candidates. Always ensure your practitioner has a reputable background and proper certification to guarantee safe and effective results.

At California Cosmetics, our dedicated team delivers this treatment in a meticulously clean and safe environment, upholding the highest standards of care.

Our Plasma Fibroblast treatments are conducted at our premier med spas located in Newport Beach and Corona, California. Visit us at our locations to immerse yourself in the transformative power of Plasma Fibroblast Therapy and embark on a path to radiant, tightened skin. Contact us to schedule an appointment or learn more about our services.

Before the procedure, we apply a topical numbing cream to minimize any sensation. The treatment involves creating small micro-injuries using the Plasma Fibroblast device, and most patients describe the feeling as mild to moderate tingling. Our aim is to ensure a relaxed and as pain-free an experience as possible for every individual undergoing the treatment.

If you are looking for more details, kindly visit Plasma Lift.